Discover the New RNA World
Optimize Every Step in Your Workflow with Our Innovative RNA Technologies
Only the Best Will Do
Discover the New RNA World
- RNA from TRIzol® in 7 Minutes
- NGS-Ready RNA from ANY Sample
- High Yield, High Purity
Scale RNA Purification with Confidence
Whether you're processing dozens of samples or thousands, automation demands more than speed. It requires uncompromising consistency.
Zymo Research's RNA preservation, purification, library preparation, and sequencing solutions are engineered to integrate seamlessly into automated workflows, delivering high-quality, DNA-free RNA across diverse sample types. The result is reproducible data you can trust to accelerate discovery, development, and translational research.
Accelerate Your Discovery With Automated Solutions
Platforms
With validated, ready-made scripts, our RNA extraction technologies are compatible with a wide array of automation platforms and industry leaders, enabling high-throughput screening across many systems.
Read our application notes with our partner platforms.
Proven Results
Explore our automated extraction chemistries in action.
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How do you extract RNA?
Comprehensive Technologies for Your RNA Research
Collection
Extraction
Preparation
Services
Sample Collection
Collection kits and devices using ground-breaking reagent technology to inactivate pathogens and protect nucleic acid content.
- Remove the need for cold chain in shipping.
- Inactive potential pathogens for safe handling.
- Easy-to-use devices available for most common sample types.
Products
Sample Preservation Reagents
DNA and RNA stabilization solutions for nucleic acids in any biological sample.
Collection Devices
DNA/RNA Shield preservation technology, provided in a variety of formats to suit a variety of sample types.
SafeCollect Devices
Spill-proof collection devices for reliable at-home sample collection.
Collection Accessories
Addons to facilitate ease of collection for complex sample types.
RNA Extraction
Discover easy-to-use RNA extraction kits for total RNA purification, including small RNAs.
Products
RNA from TRIzol® in 7 minutes
A streamlined method without phase separation or precipitation steps for the purification of high-quality RNA directly from samples in TRIzol®, TRI Reagent® or similar.
Phenol-Free RNA Extraction from Any Sample
Quick, easy, and reliable isolation of RNA from any biological sample.
RNA Clean-up from Any Reaction
Simple and reliable methods for the rapid preparation of high-quality, RT-qPCR and NGS-ready RNA.
Simultaneous DNA & RNA from Every Sample
Quick, easy, and reliable isolation of DNA & RNA from any biological or clinical sample.
Automated Purification for Every Run
High-throughput solutions for automated extraction of RNA or total nucleic acids from diverse sample inputs.
- Samples stored in TRIzol®, TRI Reagent®, or similar
- Extraction from any sample type
- Total nucleic acid extraction
Library Preparation
The Zymo-Seq RiboFree® Total RNA Library Kit enables whole transcriptome analysis for any organism.
- Universal Depletion: Novel probe-free technology depletes rRNA from any organism.
- Simplest Library Prep: Simultaneous ligation of both adapters reduces hands-on processing.
- Automation Friendly: Streamlined protocol for increased scalability.
Additionally, the Zymo-Seq SwitchFree™ 3′ mRNA Library Kit simplifies mRNA expression analysis with Unique Molecular Identifiers integrated.
Products
SwitchFree
NGS Services
RNA-Seq services that are fully customizable, from provided sample collection devices to comprehensive bioinformatic analysis.
- Free consultation for project initiation.
- Compatible with various sample types and any organism (mammals, plants, bacteria, and more)
- Comprehensive publication-ready bioinformatics analysis report
Services
RNA-Seq Analysis Service
Knowledge Center
Featured Technologies
Trusted By Leading Institutions
Testimonials from Our Customers
“ RNA extraction with the Zymo kit is simple and straight forward protocol and people who have already been using column based RNA extractions will find that this kit offers the DNase enzyme and buffers within the kit and so value for the money for the same number of samples. Even better is the genomic DNA isolation columns which is only optional in certain kits (that is sold as a separate kit with a different product number) is sold with the standard isolation protocol which is another feature I really liked. I have been isolating RNA from primary mouse and human cells for over a decade for my research work. I got introduced to this Zymo product when our lab was struggling with funding but we still could not move out of the protocols that we were already doing for many years. I have to say that Zymo product saved us a lot of money and still got reproducible good data from our work. I have become an independent investigator and currently working with a small funding. I am glad that I knew about Zymo product and continuing to use this in my experiments. I have recommended to my colleagues also. ”
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Temple University
“ This kit is very effective for RNA extraction from cells. It is easy to follow and allows inexperienced RNA users to get quality RNA on the first use - especially compared to phase separation. The on-column DNA digestion makes my workflow so much easier and the whole process takes less than 30 minutes. Tech support quickly answers any questions I have." ”
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Ohio State University
“ My research lab is mainly for undergraduates. We used to isolate RNA by using the phase separation technique. It was time-consuming, and my students often had to stop in the middle of the procedure. We also had issues with RNA quality associated with inconsistent pipetting of the aqueous phase. After a small accident during one RNA isolation, we made a switch. My students have been happier with the switch because of the reduced time needed for RNA isolation and fewer steps involved in the procedure. The quality of isolated RNA also improved significantly. The kit has saved time and money. ”
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The College of St. Scholastica
“ Direct-zol RNA Miniprep Plus Kits are great! I'm very satisfied with the efficiency/quickness of RNA extraction from human brain samples, especially when we need high quality RNA for quantification and sequencing. This product is extremely easy to use and provided a good purity of the extracted RNA. And finally, the technical support were very helpful and very responsive. ”
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College de France
“ I am very satisfied with Zymo's Quick RNA isolation kit: the protocol is easy, quick and above all, provided good RNA quality and yield from cells isolated by FACS after tissue dissociation. This is the first kit (and cheapest one!) I tested that enables me to extract sufficient RNA from a small number (5000 cells) of a particularly delicate cell type. I really appreciate that Zymo provides free samples to test the kits before purchasing them. Besides, the customer/technical service is quick to respond and always provided useful details/recommendations for my specific experiment. ”
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The Scripps Research Institute